During the Anglo-Boer War from 1899 to 1902, the British established a concentration camp on the outskirts of the village. A monument to the women and children who died during their incarceration in the camp marks the location.A little known fact about Howick (and nearby Karkloof) is that it is possibly the location of the first manned flight in the world. [3] Evidence exists that a John Goodman Household flew a self made glider in 1871 and again in 1875 on the outskirts of Howick, close to Karkloof. The actual distance flown and altitude achieved differs from source to source (some sources say the distance was 80 metres) but what can be verified is that the distance flown was further, and the duration also longer, than either of the flights made by Lilienthal or the Wright brothers. Today there exists a memorial to Household's achievement at Curry's Post, also a small distance outside Howick.

The uMngeni Valley Ranch or Nature Reserve was established in the 1970s on the then outskirts of Howick by the Wildlife and Environment Society of South Africa (WESSA). The nature reserve consists largely of the deep valley cut by the Mngeni River below the Howick Falls into the surrounding sandstone. WESSA reintroduced game into the area, such as zebra and wildebeest (gnu), and established a number of huts for overnight accommodation. In December 1996 Nelson Mandela was awarded "The Freedom of Howick". This followed his arrest some 34 years before, on 5 August 1962, on the main Durban-Johannesburg road, as it was then — more particularly, between Howick and Lidgetton West.[4] A small monument showing the site where he was arrested by the Security Police may be seen on the southern road side of the R102 in a dip in the road. In recent years Howick has expanded significantly following the establishment of a number of major retirement villages, such as Amberfield, Amberglen, Amber Valley, Amber Ridge and Amber Lakes, that flank the Karkloof Falls Road.